Report a case of cutaneous and visceral canine leishmaniasis from Querétaro, México

Resumen

RESUMEN

Leishmania infantum es el agente causal de la leishmaniasis canina cutánea y visceral, una enfermedad ampliamente descrita en varios países de Europa y América. En el presente trabajo se describe el caso de un canino raza Presa Canario nacido en México que fue remitido a consulta por una lesión alopécica en plano nasal y linfoadenomegalia generalizada. Se confirma un caso de leishmaniasis con las improntas, encontrando macrófagos con amastigotes de Leishmania. Debido al deterioro del animal se realizó la eutanasia y la necropsia. Se tomaron muestras de piel, ganglios linfáticos, hígado, riñón y bazo para realizar los análisis histológicos y moleculares. En muestras de piel, bazo y riñón se observaron lesiones granulomatosas con amastigotes y se confirma con el análisis molecular que la especie es L. infantum. El registro de este caso sugiere un riesgo potencial de esta enfermedad en una región no endémica del país.

ABSTRACT

Leishmania infantum is the causal agent of cutaneous and visceral canine leishmaniasis, a disease widely described in Europe and Latin America. This study describes a case of a canine Canary mastiff breed, born in Mexico that was referred to consult by an alopecic lesion and generalized lymph adenomegaly. Diagnosis of leishmaniasis was established by impression smears of the lesion that showed amastigotes within macrophages. Due to the poor body condition of the animal, euthanasia and necropsy were conducted and samples taken from skin, lymph nodes, liver, kidney, and spleen to perform histological and molecular analysis. In skin, spleen and kidney granulomatous lesions were observed showing amastigotes of Leishmania. The diagnosis of L. infantum was confirmed by using molecular tools. The report of this case suggests the potential risk of this disease in a non-endemic region from Mexico.